MR IMAGING OF THE DEVELOPING HUMAN BRAIN .1. PRENATAL DEVELOPMENT

被引:68
作者
HANSEN, PE
BALLESTEROS, MC
SOILA, K
GARCIA, L
HOWARD, JM
机构
[1] Department of Diagnostic Radiology, Mount Sinai Medical Center, Miami Beach
关键词
BRAIN; GROWTH AND DEVELOPMENT; MR; FETUS; CENTRAL NERVOUS SYSTEM;
D O I
10.1148/radiographics.13.1.8426929
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
To establish a baseline of the magnetic resonance (MR) imaging appearance of the fetal brain in early stages of development, the authors undertook a study of fixed and fresh specimens of embryos and fetuses of 6-28 weeks gestational age. Images of formalin-preserved and fresh specimens were comparable in their depiction of anatomic structures. On MR images of embryos of 6 weeks gestational age, the rhombic and cervical flexures, aqueduct of Sylvius, diencephalon, cerebellum, cerebral hemisphere, and fourth ventricle could be differentiated. The optic recess and chiasm, pituitary gland, pineal recess, third ventricle, pons, olfactory lobe, corpus striatum, insula, and parietal and temporal lobes could be distinguished as early as 11 weeks gestation. Although MR imaging is impractical as a screening tool for intrauterine abnormalities, it can demonstrate the fetus in great detail and allows a more specific evaluation of fetal anatomy. With the information provided by MR imaging, it may be possible to establish guidelines for assessment of the stage of development during intrauterine life.
引用
收藏
页码:21 / 36
页数:16
相关论文
共 16 条
[1]  
BARKOVICH AJ, 1990, CONT NEUROIMAGING, P77
[2]  
Bartelmez G. W., 1962, CONTRIB EMBRYOL CARN, V37, P13
[3]  
CALLEN DW, 1988, ULTRASONOGRAPHY OBST, P83
[4]   GYRAL DEVELOPMENT OF HUMAN-BRAIN [J].
CHI, JG ;
DOOLING, EC ;
GILLES, FH .
ANNALS OF NEUROLOGY, 1977, 1 (01) :86-93
[5]  
GILBERT S, 1989, PICTORIAL HUMAN EMBR, P114
[6]  
HADLOCK FP, 1983, MED ULTRASOUND, V7, P95
[7]  
LEMIRE RJ, 1975, NORMAL ABNORMAL DEV, P1
[8]   DEVELOPMENTAL STAGES OF HUMAN-BRAIN - AN MR STUDY [J].
MARTIN, E ;
KIKINIS, R ;
ZUERRER, M ;
BOESCH, C ;
BRINER, J ;
KEWITZ, G ;
KAELIN, P .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1988, 12 (06) :917-922
[9]   OBSTETRICAL MAGNETIC-RESONANCE IMAGING - FETAL ANATOMY [J].
MCCARTHY, SM ;
FILLY, RA ;
STARK, DD ;
HRICAK, H ;
BRANTZAWADZKI, MN ;
CALLEN, PW ;
HIGGINS, CB .
RADIOLOGY, 1985, 154 (02) :427-432
[10]   MR IMAGING OF FETAL BRAIN [J].
MINTZ, MC ;
GROSSMAN, RI ;
ISAACSON, G ;
THICKMAN, DI ;
KUNDEL, H ;
JOSEPH, P ;
DESIMONE, D .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1987, 11 (01) :120-123