THE RELATIONSHIP BETWEEN A NUTRITIONAL INDEX AND ACUTE PHYSIOLOGY SCORE IN CRITICAL ILLNESS

被引:6
作者
GOUGH, DB [1 ]
WHITE, M [1 ]
MORRIN, M [1 ]
JOYCE, W [1 ]
PHELAN, D [1 ]
FITZPATRICK, JM [1 ]
GOREY, TF [1 ]
机构
[1] MATER MISERICORDIAE HOSP,SURG PROFESSORIAL UNIT,47 ECCLES ST,DUBLIN 7,IRELAND
关键词
D O I
10.1007/BF02940560
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Prognostic indices derived from available physiological data (SAPS), complex nutritional and biochemical tests (PNI), grip strength and serum albumin were calculated in 16 critically ill patients receiving intravenous nutrition over a six week period. The aim was to compare these independently derived prognostic indices, to assess their response to feeding, and to determine suitability for use in Irish intensive care units. Mean SAPS (7.6+/-0.92), PNI (3.1+/-0.29),serum albumin (30.3+/-1.03 g/l) and grip strength (17.9+/-1.3%) were all suggestive of an "at risk" group. Significant associations were found between the accepted SAPS index and both PNI (r=0.6, p<0.001, n=35) and grip strength (r=-0.68, p<0.001, n=44) but not with serum albumin. No consistent improvement was seen in response to feeding in any of the derived indices. The close correlation between prognostic indices derived from either physiological, nutritional or grip strength data in this study and the failure of prognostic indices to improve during hyperalimentation would support a common mechanism, e.g. endogenous mediators, for metabolic and physiological disturbance in critical illness. It suggests that the role of hyperalimentation is supportive rather than therapeutic and re-iterates the importance of managing underlying disease processes. Simple grip strength may be a useful alternative to complex nutritional indices.
引用
收藏
页码:565 / 568
页数:4
相关论文
共 11 条
[1]  
Knaus W.A., LeGall J.R., Wagner D.P., Et al., A comparison of intensive care in the USA and France, Lancet, 2, (1982)
[2]  
Knaus W.A., Zimmerman J.E., Wagner D.P., Et al., APACHE - Acute physiology and chronic health evaluation: a physiologically based classification system, Crit Care Med, 9, pp. 591-597, (1982)
[3]  
Le, Loirat P., Alperovitch A., Et al., A simplified acute physiclogy score for ICU patients, Crit Care Med, 12, pp. 975-977, (1984)
[4]  
Knaus W.A., Draper E.A., Wagner D.P., Zimmermann JE., APACHE H: a severity of disease classification system, Crit Care Med, 13, pp. 818-829, (1985)
[5]  
Wagner D.P., Knaus W.A., Draper EA., Physiological abnormalities and outcome from acute disease: Evidence for a predictable relationship, Arch Int Med, 146, pp. 1389-1396, (1986)
[6]  
Buzby G.P., Mullen J.L., Matthews D.C., Hobbs C.L., Rosato E.F., 1980. Prognostic nutritional index in gastrointestinal surgery, Am J Surg, 139, pp. 160-167, (1986)
[7]  
Mullen J.L., Budzy G.P., Waldman T.G., Gertner M.H., Hobbs C.L., Rosato E.F., 1979. Prediction of operative morbidity and mortality by pre-operative nutritional assesment, Surgical Forum, 30, pp. 80-82, (1979)
[8]  
Casey J., Flinn W.R., Yao J.S.T., Fahey V., PawlowsKi R.D., Bergan JJ., Correlation of immune and nutritional status with wound complications in patients undergoing vascular surgery, Surgery, 93, pp. 822-827, (1983)
[9]  
Michie H.R., Spriggs D.R., Manogue K.R., Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings, Surgery, 104, pp. 280-286, (1988)
[10]  
Dinarello CA., Interleukin-1 and the pathogenesis of the acute phase response, The N Eng J Med, 311, pp. 1413-1418, (1984)