SYNTHESIS OF 13-ETHYL-11-METHYLENE-18,19-DINOR-17-ALPHA-PREGN-4-EN-20-YN-17-OL (DESOGESTREL) AND ITS MAIN METABOLITE 3-OXO DESOGESTREL

被引：25

作者：

SCHWARZ, S

RING, S

WEBER, G

TEICHMULLER, G

PALME, HJ

PFEIFFER, C

UNDEUTSCH, B

ERHART, B

GRAWE, D

机构：

[1] Division of Research and Development, Jenapharm GmbH

来源：

TETRAHEDRON | 1994年 / 50卷 / 36期

关键词：

D O I：

10.1016/S0040-4020(01)89263-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of the steroid hormone desogestrel (25) from the 18a-homo steroid 1 is described. 25 was transformed into 3-oxo desogestrel (28) by allyl oxidation.

引用

页码：10709 / 10720

页数：12

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