IN VITRO STUDY OF RAT EMBRYOS .I. EFFECTS OF DECREASED OXYGEN ON EMBRYONIC HEART RATE

被引:21
作者
SHEPARD, TH
TANIMURA, T
ROBKIN, M
机构
[1] Department of Pediatrics, Central Laboratory for Human Embryology, Seattle, Washington
[2] Department of Nuclear Engineering, University of Washington, Seattle, Washington
关键词
D O I
10.1002/tera.1420020205
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
To study directly the effects of hypoxia on the mammalian embryo, rat embryos at the 14‐, 22‐, and 35‐somite stages were explanted into the in vitro system of New. The initial heart rates in the three groups did not differ. With hypoxia the 22‐ and 35‐somite embryos responded with a prompt heart‐rate drop but no significant effect was found in the 14‐somite embryos. Irreversible sludging of yolksac circulation was associated with death in the older embryos. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company
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页码:107 / &
相关论文
共 8 条
[1]   STUDIES OF DEVELOPMENT OF CONGENITAL ANOMALIES IN EMBRYOS OF RIBOFLAVIN-DEFICIENT GALACTOFLAVIN FED RATS .2. ROLE OF TERMINAL ELECTRON TRANSPORT SYSTEMS [J].
AKSU, O ;
MACKLER, B ;
SHEPARD, TH ;
LEMIRE, RJ .
TERATOLOGY, 1968, 1 (01) :93-&
[2]   The length of heat in the albino rat as determined by the copulatory response [J].
Blandau, RJ ;
Boling, JL ;
Young, WC .
ANATOMICAL RECORD, 1941, 79 (04) :453-463
[3]  
FISHER RA, 1963, STATISTICAL TABLES
[4]  
GRABOWSKI C, 1968, J EMBRYOL EXP MORPH, V19, P347
[6]   ETIOLOGY OF HYPOXIA-INDUCED MALFORMATIONS IN CHICK EMBRYO [J].
GRABOWSKI, CT .
JOURNAL OF EXPERIMENTAL ZOOLOGY, 1964, 157 (03) :307-+
[7]  
NEW DAT, 1967, J EMBRYOL EXP MORPH, V17, P513
[8]  
NEW DAT, 1964, J EMBRYOL EXP MORPH, V12, P101