PINEAL N-ACETYLTRANSFERASE ACTIVITY IN HAMSTERS MAINTAINED IN SHORTENED LIGHT CYCLES

被引：7

作者：

RUDEEN, PK ^{[1
]}

REITER, RJ ^{[1
]}

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT ANAT,SAN ANTONIO,TX 78284

来源：

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 1979年 / 2卷 / 01期

关键词：

light-dark cycles; N-acetyltransferase; pineal gland;

D O I：

10.1007/BF03349271

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pineal serotonin N-acetyltransferase activity (NAT) was compared among Syrian hamsters maintained in light: dark (LD) cycles of 14:10 or 2:22 or in an interrupted (LD 1/4:5 3/4 × 4) photoperiodic cycle. In hamsters maintained in a LD 14:10 photoperiod, the zenith of pineal NAT activity occurs at 04:00 h, approximately 8 hours after the onset of the dark phase. When the onset of the dark phase was advanced by 8 hours (in hamsters maintained in LD 2:22 cycles), the pineal NAT activity was advanced by an equivalent length of time. Hamster pineal NAT activity was sup-pressed throughout a 24-hour period when the animals were maintained in darkness interrupted with brief periods of light at 6 h intervals (LD 1/4:5 3/4 × 4). The results suggest that melatonin syn-thesis is determined according to when light occurs during the photoperiodic cycle rather than by the total amount of darkness or the dark: light ratio to which animals are exposed in a 24-hour period. © 1979, Italian Society of Endocrinology (SIE). All rights reserved.

引用

页码：19 / 23

页数：5

共 19 条

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