HOMEOTIC GENES AND THE EVOLUTION OF ARTHROPODS AND CHORDATES

被引:538
作者
CARROLL, SB
机构
[1] Howard Hughes Medical Institute, University of Wisconsin at Madison, R. M. Bock Laboratories, Madison, WI, 53706
关键词
D O I
10.1038/376479a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Clusters of homeotic genes sculpt the morphology of animal body plans and body parts. Different body patterns may evolve through changes in homeotic gene number, regulation or function. Recent evidence suggests that homeotic gene clusters were duplicated early in vertebrate evolution, but the generation of arthropod and tetrapod diversity has largely involved regulatory changes in the expression of conserved arrays of homeotic genes and the evolution of interactions between homeotic proteins and the genes they regulate.
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页码:479 / 485
页数:7
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