REGULATION OF RAT-LIVER PHOSPHOFRUCTOKINASE LEVELS IN MORRIS HEPATOMAS

被引：5

作者：

DUNAWAY, GA ^{[1
]}

LEUNG, GLY ^{[1
]}

THRASHER, JR ^{[1
]}

NAQUI, D ^{[1
]}

MORRIS, HP ^{[1
]}

机构：

[1] HOWARD UNIV,COLL MED,CANC RES CTR,WASHINGTON,DC 20059

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 88卷 / 03期

关键词：

D O I：

10.1016/0006-291X(79)91491-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The levels of the major liver phosphofructokinase isozyme (PFK-L2) and the PFK regulatory factor were measured in adult and fetal liver as well as Morris hepatomas of different differentiation states. The results indicate that both the PFK-L2 activity and the PFK regulatory factor levels in well and highly differentiated hepatomas are not statistically different from the amounts found in adult liver. In the poorly differentiated hepatomas and fetal liver, the levels of both PFK-L2 and PFK regulatory factor are approximately 2 and 3 fold greater, respectively, than what was found in adult liver. © 1979.

引用

页码：882 / 886

页数：5

共 9 条

[1]

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[2]

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[3]

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[4] SYNTHESIS AND DEGRADATION OF MAJOR HEPATIC PHOSPHOFRUCTOKINASE ISOENZYME IN RAT-LIVER AND HEPATOMA 3924-A [J].

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[5] INCREASED PHOSPHOFRUCTOKINASE CONCENTRATION IN HEPATOMA 3924-A - ENZYMIC AND IMMUNOLOGICAL EVIDENCE [J].

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[6] COMPARISON OF PHOSPHOFRUCTOKINASE ISOENZYME PROFILES OF TRANSPLANTABLE HEPATOMAS AND NORMAL LIVER [J].

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[7]

KNOX WE, 1972, ENZYME PATTERNS FETA

[8] MULTIPLE FORMS OF PHOSPHOFRUCTOKINASE IN RAT TISSUES AND RAT TUMORS [J].

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SUGIMURA, T ;

MATSUSHIMA, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1972, 48 (03) :473-+

[9]

WEINHOUSE JB, 1978, MORRIS HEPATOMAS MEC, P44

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