A ONE-POT SYNTHESIS OF COUMARYL, CONIFERYL AND SINAPYL ALCOHOL

被引：11

作者：

ROTHEN, L ^{[1
]}

SCHLOSSER, M ^{[1
]}

机构：

[1] UNIV LAUSANNE,INST CHIM ORGAN,RUE BARRE 2,CH-1005 LAUSANNE,SWITZERLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(00)74358-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The side chain of 4-allylphenol can be easily deprotonated if the butyllithium/potassium tert-butoxide superbase is employed. Consecutive treatment with fluorodimethoxyboron and hydrogen peroxide affords directly 3-(4-hydroxy-phenyl)-2-propen-1-ol (''coumaryl alcohol''). In the same way, 4-allyl-2-methoxyphenol can be converted to coniferyl alcohol and 4-allyl-2,6-dimethoxyphenol to sinapyl alcohol.

引用

页码：2475 / 2476

页数：2

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