H-Y-ANTIGEN IN 46,XY PURE TESTICULAR DYSGENESIS

被引：14

作者：

NAZARETH, HRS ^{[1
]}

MOREIRAFILHO, CA ^{[1
]}

CUNHA, AJB ^{[1
]}

VIEIRAFILHO, JPB ^{[1
]}

LENGYEL, AMJ ^{[1
]}

LIMA, MC ^{[1
]}

机构：

[1] UNIV SAO PAULO, DEPT BIOL, HUMAN GENET LAB, SAO PAULO 01000, SP, BRAZIL

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1979年 / 3卷 / 02期

关键词：

D O I：

10.1002/ajmg.1320030206

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Clinical, cytogenetic, pathologic, and histocompatibility-Y (H-Y) antigen studies were performed on a phenotypic female with primary amenorrhea and streak gonads. Pathological examination of tissues removed at total hysterectomy and bilateral salpingo-gonadectomy showed gonadoblastoma and dysgerminoma of left streak. A single F-body (Y chromosome) was found in buccal smears. Analysis of blood cells and tumor fibroblasts showed a 46,XY chromosome constitution (Q-banding). The data were consistent with a diagnosis of 46,XY pure testicular dysgenesis. Positive results for H-Y antigen were found in this case.

引用

页码：149 / 154

页数：6

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