INHIBITION OF NORFLOXACIN ABSORPTION BY DAIRY-PRODUCTS

被引：36

作者：

KIVISTO, KT

OJALAKARLSSON, P

NEUVONEN, PJ

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1992年 / 36卷 / 02期

关键词：

D O I：

10.1128/AAC.36.2.489

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Seven healthy subjects received, after an overnight fast, a single 200-mg oral dose of norfloxacin with water, whole milk, and unflavored yoghurt. Coadministration of milk or yoghurt reduced the extent of norfloxacin absorption and the mean peak concentration in plasma by approximately 50%. Taking of norfloxacin with these liquid dairy products should be avoided.

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页码：489 / 491

页数：3

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