DEPROTECTION OF SILYL ETHERS USING 2,3-DICHLORO-5,6-DICYANO-P-BENZOQUINONE

被引：77

作者：

TANEMURA, K ^{[1
]}

SUZUKI, T ^{[1
]}

HORAGUCHI, T ^{[1
]}

机构：

[1] NIIGATA UNIV,FAC SCI,DEPT CHEM,NIIGATA 95021,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 22期

关键词：

D O I：

10.1039/p19920002997

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the presence of a catalytic amount of 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), triethylsilyl (TES) and tert-butyldimethylsilyl (TBDMS) ethers are readily hydrolysed to the corresponding alcohols in MeCN-H2O (9:1) or tetrahydrofuran (THF)-H2O (9:1). TES ethers are cleaved to alcohols more easily than TBDMS ethers. tert-Butyldiphenylsilyl (TBDPS) ethers are stable under these reaction conditions.

引用

页码：2997 / 2998

页数：2

共 15 条

[1]

Adkins H., 1931, J AM CHEM SOC, V53, P1095

[2]

Colvin E. W., 1981, SILICON ORGANIC SYNT

[3] NEW SYNTHETIC APPROACH TO PROSTANOIDS VIA CYCLOPENTENE VINYLATION [J].