MALIGNANT PERITONEAL MESOTHELIOMA IN A 17-YEAR-OLD BOY WITH EVIDENCE OF PREVIOUS EXPOSURE TO CHRYSOTILE AND TREMOLITE ASBESTOS

被引：7

作者：

ANDRION, A

BOSIA, S

PAOLETTI, L

FEYLES, E

LANFRANCO, C

BELLIS, D

MOLLO, F

机构：

[1] CITY HOSP ASTI,DIV OCCUPAT MED,I-14100 ASTI,ITALY

[2] CITY HOSP ASTI,DIV INTERNAL MED,I-14100 ASTI,ITALY

[3] IST SUPER SANITA,ULTRASTRUCT LAB,I-00161 ROME,ITALY

[4] UNIV TURIN,SCH MED,DEPT BIOMED SCI & ONCOL,PATHOL ANAT SECT,TURIN,ITALY

[5] S GIOVANNI HOSP,TURIN,ITALY

来源：

HUMAN PATHOLOGY | 1994年 / 25卷 / 06期

关键词：

D O I：

10.1016/0046-8177(94)90230-5

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We describe a case of malignant peritoneal mesothelioma arising in a 17-year-old boy. The diagnosis was based on a comprehensive study including light microscopy, histochemistry, immunohistochemistry, evaluation of the clinical course, and autopsy examination. Analytical transmission electron microscopy showed a concentration of 510,000 asbestos fibers/g dry lung tissue. The fibers were represented by chrysotile (62%) and tremolite (38%) asbestos. About 40% of the total fibers were longer than 5 μm. The presence of tremolite fibers was probably due to environmental exposure to contamined cosmetic talc. This is the first reported case of pathologically proven exposure to asbestos dust in malignant mesothelioma of childhood and adolescence. © 1994.

引用

页码：617 / 622

页数：6

共 38 条

[1]

BEDROSSIAN CWM, 1992, SEMIN DIAGN PATHOL, V9, P91

[2]

BELLOCQ J P, 1989, Archives d'Anatomie et de Cytologie Pathologiques, V37, P240

[3] FIBER SIZE AND NUMBER IN WORKERS EXPOSED TO PROCESSED CHRYSOTILE ASBESTOS, CHRYSOTILE MINERS, AND THE GENERAL-POPULATION [J].