NUCLEOTIDE-SEQUENCE OF A REGION OF HUMAN MITOCHONDRIAL-DNA CONTAINING THE PRECISELY IDENTIFIED ORIGIN OF REPLICATION

被引:132
作者
CREWS, S
OJALA, D
POSAKONY, J
NISHIGUCHI, J
ATTARDI, G
机构
[1] Division of Biology, California Institute of Technology, Pasadena
关键词
D O I
10.1038/277192a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A fragment of HeLa cell mitochondrial DNA containing the origin of replication has been sequenced. The precise position of the origin in this sequence has been identified by determining the nucleotide order in the 5′-end proximal portion of the heavy strand initiation fragment (7S DNA), and by aligning the two sequences. © 1979 Nature Publishing Group.
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页码:192 / 198
页数:7
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