MANAGEMENT OF NONSTAPHYLOCOCCAL TOXIC EPIDERMAL NECROLYSIS - FOLLOW-UP-STUDY OF 16 CASE-HISTORIES

被引：29

作者：

TEGELBERGSTASSEN, MJAM ^{[1
]}

VANVLOTEN, WA ^{[1
]}

DELAFAILLE, HB ^{[1
]}

机构：

[1] STATE UNIV UTRECHT HOSP, DEPT DERMATOL, 3511 GV UTRECHT, NETHERLANDS

来源：

DERMATOLOGICA | 1990年 / 180卷 / 03期

关键词：

corticosteroids; reverse barrier nursing; toxic epidermal necrolysis;

D O I：

10.1159/000248010

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In this study the clinical and laboratory data of 14 patients who experienced 16 attacks of nonstaphylococcal toxic epidermal necrolysis (TEN) are presented. All patients were treated in the Department of Dermatology of the University Hospital of Utrecht. Only 1 patient died. Attention is focused on a successful management consisting of reversed barrier nursing, painstakingly executed skin care, timely use of antibiotics and a therapy consisting of high dosages of corticosteroids. Thorough management in centers experienced in the treatment of TEN is essential for good treatment results. Further investigations concerning the use of corticosteroids in treating TEN are needed.

引用

页码：124 / 129

页数：6

共 28 条

[1] ABERER W, 1982, HAUTARZT, V33, P484
[2] Achten G, 1970, Arch Belg Dermatol Syphiligr, V26, P97
[3] TOXIC EPIDERMAL NECROLYSIS - RAPID DIFFERENTIATION BETWEEN STAPHYLOCOCCAL AND DRUG-INDUCED DISEASE
AMON, RB
DIMOND, RL
[J]. ARCHIVES OF DERMATOLOGY, 1975, 111 (11) : 1433 - 1437
[4] BOMBAL C, 1983, ANN DERMATOL VENER, V110, P113
[5] STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS IN A PATIENT WITH SYSTEMIC LUPUS-ERYTHEMATOSUS
BURGE, SM
DAWBER, RPR
[J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1985, 13 (04) : 665 - 666
[6] ALLOPURINOL-INDUCED TOXIC EPIDERMAL NECROLYSIS
DAN, M
JEDWAB, M
PELED, M
SHIBOLET, S
[J]. INTERNATIONAL JOURNAL OF DERMATOLOGY, 1984, 23 (02) : 142 - 144
[7] TOXIC EPIDERMAL NECROLYSIS, LEUCOPENIA AND THROMBOCYTOPENIC PURPURA - A FURTHER COMPLICATION OF BENOXAPROFEN THERAPY
FENTON, DA
ENGLISH, JS
[J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1982, 7 (03) : 277 - 279
[8] INTENSIVE THERAPY UNIT MANAGEMENT OF TOXIC EPIDERMAL NECROLYSIS - PRACTICAL ASPECTS
FINLAY, AY
RICHARDS, J
HOLT, PJA
[J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1982, 7 (01) : 55 - 60
[9] GILLIAM JN, 1982, CLIN RHEUM DIS, V8, P207
[10] HEMATOLOGICAL DISTURBANCES AND IMMUNE-MECHANISMS IN TOXIC EPIDERMAL NECROLYSIS
GOENS, J
SONG, M
FONDU, P
BLUM, D
ACHTEN, G
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1986, 114 (02) : 255 - 259

← 1 2 3 →