SYNGENEIC BONE-MARROW TRANSPLANTATION AND ADOPTIVE TRANSFER OF PERIPHERAL-BLOOD LYMPHOCYTES COMBINED WITH ZIDOVUDINE IN HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) INFECTION

被引：77

作者：

LANE, HC

ZUNICH, KM

WILSON, W

CEFALI, F

EASTER, M

KOVACS, JA

MASUR, H

LEITMAN, SF

KLEIN, HG

STEIS, RG

LONGO, DL

FAUCI, AS

机构：

[1] Building 10, National Institutes of Health, Bethesda

来源：

ANNALS OF INTERNAL MEDICINE | 1990年 / 113卷 / 07期

关键词：

D O I：

10.7326/0003-4819-113-7-512

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Although they establish the feasibility of combining zidovudine with cellular immune reconstitution in treating of patients with HIV infection, our results show that any benefits from such combination therapy are at best transient. Future attempts at cellular immune reconstitution may need to use improved antiretroviral regimens as well as immunization of donors with HIV-specific antigens.

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页码：512 / 519

页数：8

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