SUPEROXIDE PRODUCTION BY PHAGOCYTES - ANOTHER LOOK AT THE EFFECT OF CYTOCHROME-C ON OXYGEN-UPTAKE BY STIMULATED NEUTROPHILS

被引：15

作者：

BABIOR, BM ^{[1
]}

机构：

[1] TUFTS UNIV,NEW ENGLAND MED CTR,DEPT MED,BOSTON,MA 02111

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 91卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)90606-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The widely held view that stimulated phagocytes liberate O2- into the extracellular medium is supported by the alterations in oxygen uptake which occur when ferricytochrome c is added to a suspension of zymosan-treated neutrophils. An explanation consistent with this view is provided for some previously reported results (FEBS Lett. 100, 27) which initially appeared to conflict with the notion that O2- is released by phagocytes. © 1979.

引用

页码：222 / 226

页数：5

共 9 条

[1] PARTICULATE SUPEROXIDE-FORMING SYSTEM FROM HUMAN NEUTROPHILS - PROPERTIES OF SYSTEM AND FURTHER EVIDENCE SUPPORTING ITS PARTICIPATION IN RESPIRATORY BURST
BABIOR, BM
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[2] OXYGEN-DEPENDENT MICROBIAL KILLING BY PHAGOCYTES .1.
BABIOR, BM
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (12) : 659 - 668
[3] BIOLOGICAL DEFENSE MECHANISMS - PRODUCTION BY LEUKOCYTES OF SUPEROXIDE A POTENTIAL BACTERICIDAL AGENT
BABIOR, BM
KIPNES, RS
CURNUTTE, JT
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1973, 52 (03) : 741 - 744
[4] DEFECTIVE SUPEROXIDE PRODUCTION BY GRANULOCYTES FROM PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE
CURNUTTE, JT
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BABIOR, BM
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1974, 290 (11) : 593 - 597
[5] NADPH OXIDASE DEFICIENCY IN X-LINKED CHRONIC GRANULOMATOUS DISEASE
HOHN, DC
LEHRER, RI
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1975, 55 (04) : 707 - 713
[6] KLEBANOFF SJ, 1978, NEUROPHIL FUNCTION C, P294
[7] H2O2 RELEASE FROM HUMAN GRANULOCYTES DURING PHAGOCYTOSIS RELATIONSHIP TO SUPEROXIDE ANION FORMATION AND CELLULAR CATABOLISM OF H2O2 - STUDIES WITH NORMAL AND CYTOCHALASIN B-TREATED CELLS
ROOT, RK
METCALF, JA
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1977, 60 (06) : 1266 - 1279
[8] PRODUCTION OF SUPEROXIDE BY NEUTROPHILS - REAPPRAISAL
SEGAL, AW
MESHULAM, T
[J]. FEBS LETTERS, 1979, 100 (01) : 27 - 32
[9] WEENING RS, 1975, J LAB CLIN MED, V85, P245

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