ENHANCEMENT OF RESISTANCE TO BACTERIAL-INFECTION IN MICE BY VITAMIN-B-2

被引：32

作者：

ARAKI, S

SUZUKI, M

FUJIMOTO, M

KIMURA, M

机构：

[1] Research and Development Division, Eisai Co., Ltd., Tsukuba, Ibaraki 300-26, Tokodai

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 1995年 / 57卷 / 04期

关键词：

IMMUNOSTIMULANT; VITAMIN-B-2;

D O I：

10.1292/jvms.57.599

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

We found that the intramuscular injection of vitamin B-2 enhanced host resistance to E. coli infection in a dose-dependent manner (6.25 mg/kg-100 mg/kg). Furthermore, VB2 exhibited the protective activity against Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Actinobacillus pleuropneumoniae. The mechanism of action of VB2 for enhancing resistance in mice may be, at least in part, its ability to stimulate the multiplication of neutrophils and monocytes, and to activate macrophages.

引用

收藏

页码：599 / 602

页数：4

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