SERIAL STUDIES OF SERUM DOPAMINE-B-HYDROXYLASE AND URINARY VANILLYLMANDELIC AND HOMOVANILLIC ACIDS IN NEURO-BLASTOMA

被引：7

作者：

BREWSTER, MA

BERRY, DH

机构：

[1] Departments of Pathology and Pediatrics, University of Arkansas, Medical Sciences, Little Rock

来源：

MEDICAL AND PEDIATRIC ONCOLOGY | 1979年 / 6卷 / 02期

关键词：

DBH inhibitors; dopamine‐B‐hydroxylase; homovanillic acid; neuroblastoma;

D O I：

10.1002/mpo.2950060202

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent reports have suggested that elevations of serum dopamine‐B‐hydroxylase (DBH) activity may correlate with diagnosis in neuroblastoma patients excreting vanillylmandelic acid (VMA). We have serially studied serum DBH and urinary homovanillic acid (HVA) and VMA excretion during the disease course of five patients with neuroblastoma. DBH activities did not indicate clinical course, therapies, or prognosis. Dilution studies revealed an age‐related alteration in DBH effectors and they suggest that these may be different in neuroblastoma. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：93 / 99

页数：7

共 20 条

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