HUMAN HERPESVIRUS-6 INFECTION AND BONE-MARROW TRANSPLANTATION

被引：9

作者：

YOSHIKAWA, T

KOJIMA, S

ASANO, Y

机构：

[1] Department of Pediatrics, Fujita Health University School of Medicine, Toyoake

[2] Division of Hematology-Oncology, Children's Medical Center, Japanese Red Cross Nagoya First Hospital, Nagoya

来源：

LEUKEMIA & LYMPHOMA | 1992年 / 8卷 / 1-2期

关键词：

HERPESVIRUS-6; BMT; TRANSPLANTATION;

D O I：

10.3109/10428199209049819

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human herpesvirus-6 (HHV-6) is ubiquitous in the human population and causes exanthem subitum, a benign disease seen in infancy. However it also produces a wide spectrum of clinical manifestations including cases with a fatal outcome. The virus remains latent in several organs, including the kidneys, liver, lymph/nodes and salivary glands, after the primary infection and reactivates when immune function is impaired. Reactivation of the virus occurred in a half of the bone marrow recipients 2 to 4 weeks after bone marrow transplantation (BMT). It remains to be established whether HHV-6 in fact causes the fever and rash observed in recipients who have reactivation of the virus. The data reviewed here will be required to compare with those of human herpesvirus 7 and a different group of HHV-6.

引用

页码：65 / 73

页数：9

共 70 条

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