DIRECT RESOLUTION OF RACEMIC DRUGS USING CELLULASE SILICA AS A CHIRAL STATIONARY-PHASE

被引：7

作者：

BLOM, Y

HELDIN, E

机构：

[1] Medical Products Agency, Division of Pharmacy, S-75103 Uppsala

来源：

JOURNAL OF CHROMATOGRAPHY A | 1993年 / 653卷 / 01期

关键词：

D O I：

10.1016/0021-9673(93)80402-T

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The enantiomers of propafenone, flecainide and its two analogues 4-hydroxyflecainide and 5-hydroxyflecainide, betaxolol, doxazosin, and terazosin and its analogue A-65297 were separated on a cellulase silica column (TrichSep-100). The effects of pH and the concentration of the organic modifier, 2-propanol, were studied.

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页码：138 / 143

页数：6

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