DIRECT RESOLUTION OF ENANTIOMERS IN COLUMN LIQUID-CHROMATOGRAPHY

被引：76

作者：

AUDEBERT, R

机构：

[1] Laboratoire de Physico-Chimie Macromoleculaire, l'Universite Pierre et Marie Curie (Paris VI), rue Vauquelin - 75231 Paris Cedex 05

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1979年 / 2卷 / 08期

关键词：

D O I：

10.1080/01483917908060125

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Important progress has been performed during the ten past years, in the direct resolution (without derivatization) of enantiomers by column liquid chromatography. Generally chiral packings proceeding from natural or synthetic optically active polymers are used. Complete resolutions of hole families of chiral solutes is obtained in systems involving a steric locking interaction (charge transfer between aromatic substituents, crown ether cavity, crowded complexes with metal ions). For analytical purposes an other promising way is the use of a classical packing and a chiral mobile phase. © 1979, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：1063 / 1095

页数：33

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