MODIFICATION OF KIDNEY IMMUNOGENICITY WITH STANDARD CONCANAVALIN-A AND ITS SUBFRACTIONS

被引：7

作者：

TOLEDOPEREYRA, LH

RAMAKRISHNAN, VR

机构：

[1] Department of Surgery, Section of Transplantation and Surgical Research, Henry Ford Hospital, Detroit, MI

来源：

IMMUNOLOGICAL COMMUNICATIONS | 1979年 / 8卷 / 02期

关键词：

D O I：

10.3109/08820137909048680

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pretreatment of kidneys with purified Concanavalin A (25mg/L) allowed for a significant prolongation of survival after allotransplantation in minimally immunosuppressed mongrel dogs. Kidneys pretreated with standard Concanavalin A, impure fraction or the lipopolysaccharide had no prolongation of survival. In fact, the impure fraction and the lipopolysaccharide showed a diminished transplant kidney survival. These studies confirm the beneficial effect of Concanavalin A when the purified form is utilized in modifying kidney allograft survival. © 1979 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：167 / 172

页数：6

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