EFFECT OF ERYTHROCYTE PROTOPORPHYRIN ON BLOOD MANGANESE IN LEAD-EXPOSED CHILDREN AND ADULTS

被引：8

作者：

WIBOWO, AAE

SALLE, HJA

CASTILHO, PD

ZIELHUIS, RL

机构：

[1] Coronel Laboratory for Occupational and Environmental Health, Faculty of Medicine, University of Amsterdam, Amsterdam

来源：

INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 1979年 / 43卷 / 03期

关键词：

Blood lead; Blood manganese; Erythrocyte porphyrin;

D O I：

10.1007/BF00381189

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In one study in 2- and 3-year-old children (geom. average 143 μg Pb/1) and in two studies in workers (geom. average 483 pg Pb/1 and 323 μg Pb/1) manganese in blood levels increased with blood lead and with free erythrocyte porphyrin (FEP). The zero-order correlation between PbB and MnB disappeared when FEP was kept constant. The conclusion is drawn that the increase of MnB with increasing PbB is probably not due to simultaneous exposure, neither to direct interaction between Pb and Mn, but mediated through a relationship between Mn and porphyrin in erythrocytes. © 1979 Springer-Verlag.

引用

页码：177 / 182

页数：6

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