TRANSFERS OF FROZEN - THAWED HUMAN EMBRYOS IN CYCLES STIMULATED BY HMG

被引：18

作者：

LORNAGE, J

BOULIEU, D

MATHIEU, C

GUERIN, JF

PINATEL, MC

JAMES, R

ALVARADO, C

机构：

[1] Laboratoire de Biologie, La Reproduction et du Développement, 69437 Lyon Cedex 03, Place d'Arsonval

[2] Clinique de Gynécologic L'H6pital Edouard Herriot, 69437 Lyon Cedex 03, Place d'Arsonval

来源：

HUMAN REPRODUCTION | 1990年 / 5卷 / 01期

关键词：

Analogue; Cryopreservation; Human embryo quality; LHRH;

D O I：

10.1093/oxfordjournals.humrep.a137042

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A total of 130 transfers of frozen-thawed (F-T) human embryos was carried out after moderate ovarian stimulation with human menopausal gonadotrophin (HMG). Embryos were replaced 3 days after the spontaneous luteinizing hormone (LH) surge or 4 days if ovulation was induced by human chorionic gonadotrophin (HCG). Embryos were thawed a few hours prior to transfer. One-hundred-and-twenty-three transfers were effective and 23 pregnancies were achieved. The rate of ongoing pregnancies per transfer was 17.9% (22/123). The survival rate of embryos originating from cycles stimulated by a combination of an LHRH analogue and HMG in a long protocol (LA-HMG protocol) was significantly lower when compared with the rate of embryos retrieved from clomiphene citrate-HMG (CC-HMG protocol) stimulated cycles (52 versus 67%, P > 0.05). When fresh embryos originated from cycles stimulated with an LHRH analogue and HMG in a short protocol (SA-HMG protocol), the survival rate was not affected (59 versus 67%, NS). Although the difference was not significant, the ongoing pregnancy rate per transfer according to the three protocols from which the embryos originated seemed to be better with the SA-HMG protocol: 16% with the CC-HMG protocol, 14.5% with the LA-HMG protocol versus 27.6% with the SA-HMG protocol The success rate was independent of the number of F-T transferred embryos if at least one embryo with 100% intact blastomeres was replaced. © 1990 Oxford University Press.

引用

页码：60 / 65

页数：6

共 24 条

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