PULMONARY-HYPERTENSION ASSOCIATED WITH LONG-STANDING THROMBOCYTOSIS

被引：27

作者：

ROSTAGNO, C

PRISCO, D

ABBATE, R

POGGESI, L

机构：

[1] Clinica Medica I, Universita Firenze, Florence

来源：

CHEST | 1991年 / 99卷 / 05期

关键词：

D O I：

10.1378/chest.99.5.1303

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A case of thromboembolic pulmonary hypertension associated with long-standing thrombocytosis is presented. In this patient we found a significant local pulmonary platelet activation and thrombin generation as indicated by the existence of a transpulmonary gradient for thromboxane A2, beta thromboglobulin and fibrinopeptide A. Prolonged heparin and acetylsalicylic acid treatment resulted in improvement of clinical and hemodynamic conditions. These findings support the usefulness of anticoagulating and antiaggregating therapy in selected cases of pulmonary hypertension.

引用

页码：1303 / 1305

页数：3

共 22 条

[1]

BARST RS, 1985, CHEST S, V88, pS416

[2] PRIMARY PULMONARY-HYPERTENSION - A HISTOPATHOLOGIC STUDY OF 80 CASES [J].