CHROMOSOMAL ANALYSIS OF PREGNANCY LOSSES IN PATIENTS UNDERGOING ASSISTED REPRODUCTION

被引:7
作者
SHIELDS, LE [1 ]
SERAFINI, PC [1 ]
SCHENKEN, RS [1 ]
MOORE, CM [1 ]
机构
[1] UNIV TEXAS,HLTH SCI CTR,DEPT OBSTET & GYNECOL,DIV REPROD ENDOCRINOL & INFERTIL,SAN ANTONIO,TX 78284
关键词
INVITRO FERTILIZATION; EARLY PREGNANCY LOSS; CHROMOSOMAL ANALYSIS;
D O I
10.1007/BF01204116
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Chromosomal analysis was performed on products of conception from 18 patients having early pregnancy loss after assisted reproduction. Sonographic findings prior to obtaining tissue varied from gestational sacs consistent with a blighted ovum to fetal poles with cardiac activity. The mean age of the patients was 36.3 years. There were nine (50%) normal karyotypes, five (28%) autosomal trisomies, two cases of tetraploidy, one case of monosomy, and a case with two pericentric inversions. The results of this study suggest that patients undergoing assisted reproduction are not at an increased risk for chromosomal abnormalities.
引用
收藏
页码:57 / 60
页数:4
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