USE OF COLUMN SWITCHING FOR THE DETERMINATION OF NIACINAMIDE IN COMPOUND FEED

被引：9

作者：

BALSCHUKAT, D

KRESS, E

机构：

[1] Degussa AG, Industrial and Fine Chemicals Division, Application and Technical Service, D-6450 Hanau

来源：

JOURNAL OF CHROMATOGRAPHY | 1990年 / 502卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(01)89565-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-performance liquid chromatographic method is described for the determination of niacinamide in compound feed. The niacinamide is extracted with 0.2 M hydrochloric acid in order to suppress the hydrolysis of the niacinamide to nicotinic acid. The chromatography is carried out with the aid of column switching. An RP-18 column is used for the preseparation, and the analytical separation takes place in a cation-exchange column. With the proposed method, the limit of determination is about 2 ppm of niacinamide. © 1990.

引用

页码：79 / 85

页数：7

共 17 条

[1]

BALSCHUKAT D, 1988, LANDWIRT FORSCH, V41, P120

[2]

CALLMER K, 1974, Chromatographia, V7, P644, DOI 10.1007/BF02290508

[3] APPLICATIONS OF COLUMN-SWITCHING TECHNIQUE IN BIOPHARMACEUTICAL ANALYSIS .1. HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF AMITRIPTYLINE AND ITS METABOLITES IN HUMAN-PLASMA [J].