GENETIC SIMILARITY OF INTESTINAL SPIROCHETES FROM HUMANS AND VARIOUS ANIMAL SPECIES

被引：46

作者：

KOOPMAN, MBH

KASBOHRER, A

BECKMANN, G

VANDERZEIJST, BAM

KUSTERS, JG

机构：

[1] UNIV UTRECHT, SCH VET MED,INST INFECT DIS & IMMUNOL, DEPT BACTERIOL,POB 80165, 3508 TD UTRECHT, NETHERLANDS

[2] BUNDESGESUNDHEITSAMT, AIDS ZENTRUM, W-1000 BERLIN 65, GERMANY

[3] TIERARZTL HSCH HANNOVER, INST MIKROBIOL & TIERSEUCHEN, W-3000 HANNOVER, GERMANY

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1993年 / 31卷 / 03期

关键词：

D O I：

10.1128/JCM.31.3.711-716.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The chromosomal DNA of spirochetes isolated from human, swine, dog, mouse, rat, and chicken intestine or feces was subjected to restriction enzyme analysis and hybridization with three different DNA probes, derived from a flagellin gene, a hemolysin gene, and the 16S rDNA sequence of the pathogenic swine intestinal spirochete Serpulina hyodysenteriae. This genetic analysis showed that intestinal spirochetes represent a heterogenous but related population of bacteria. In general, unique genotypes were distinguished among isolates from the same host species; they were not present among isolates from other host species. This suggests the host specificity of some strains. An exception to this are isolates from humans and dogs suffering from gastrointestinal disorders; these isolates showed highly similar or even identical genotypes. None of them resembled any of the genotypes of isolates found in other host species without apparent disease.

引用

页码：711 / 716

页数：6

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