LONG-TERM FOLLOW-UP OF PATIENTS WITH DUCHENNE MUSCULAR-DYSTROPHY RECEIVING VENTILATORY SUPPORT

被引：11

作者：

FUKUNAGA, H ^{[1
]}

OKUBO, R ^{[1
]}

MORITOYO, T ^{[1
]}

KAWASHIMA, N ^{[1
]}

OSAME, M ^{[1
]}

机构：

[1] DEPT INTERNAL MED 3,KAGOSHIMA,JAPAN

来源：

MUSCLE & NERVE | 1993年 / 16卷 / 05期

关键词：

DUCHENNE MUSCULAR DYSTROPHY; RESPIRATORY FUNCTION; NEGATIVE CHEST RESPIRATOR; NIGHT VENTILATION; OXIMETER;

D O I：

10.1002/mus.880160519

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We, retrospectively, examined the clinical course, decline in pulmonary function, and requirements for ventilatory assistance in 54 patients with Duchenne-type muscular dystrophy (DMD) who were followed in the muscle disease ward of the National Hospital in Kagoshima, Japan, over the past 20 years. The percentage of the predicted vital capacity (%VC) declined in relation to age and stage of disease. Most patients required assisted ventilation when the %VC fell below 10%. Twenty patients were treated with a negative pressure chest respirator. Six of these died at the mean age of 23.2 years after being on the respirator for a mean period of 18 months. Fourteen patients are surviving at a mean age of 23.5 years after being on the respirator for a mean period of 39 months.

引用

页码：554 / 558

页数：5

共 9 条

[1]

BACH J, 1981, ARCH PHYS MED REHAB, V62, P328

[2] DECLINE IN RESPIRATORY-FUNCTION AND EXPERIENCE WITH LONG-TERM ASSISTED VENTILATION IN ADVANCED DUCHENNES MUSCULAR-DYSTROPHY [J].