WATER-DEPRIVATION IN THE RAT INDUCES NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION IN THE HYPOTHALAMIC PARAVENTRICULAR AND SUPRAOPTIC NUCLEI

被引：85

作者：

UETA, Y ^{[1
]}

LEVY, A ^{[1
]}

CHOWDREY, HS ^{[1
]}

LIGHTMAN, SL ^{[1
]}

机构：

[1] UNIV BRISTOL,BRISTOL ROYAL INFIRM,DEPT MED,BRISTOL BS2 8HW,AVON,ENGLAND

来源：

NEUROSCIENCE RESEARCH | 1995年 / 23卷 / 03期

关键词：

WATER DEPRIVATION; NITRIC OXIDE SYNTHASE; PARAVENTRICULAR NUCLEUS; SUPRAOPTIC NUCLEUS; SUBFORNICAL ORGAN; RAT;

D O I：

10.1016/0168-0102(95)00956-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We examined the effects of water deprivation on nitric oxide synthase (NOS) gene expression in the rat hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), using in situ hybridization histochemistry. Dehydration caused a significant increase in NOS gene transcripts in the PVN and SON but not in the subfornical organ (SFO). The results suggest that dehydration has a major effect on the NOS gene expression in the PVN and SON.

引用

页码：317 / 319

页数：3

共 13 条

[1] CLONED AND EXPRESSED NITRIC-OXIDE SYNTHASE STRUCTURALLY RESEMBLES CYTOCHROME-P-450 REDUCTASE
BREDT, DS
HWANG, PM
GLATT, CE
LOWENSTEIN, C
REED, RR
SNYDER, SH
[J]. NATURE, 1991, 351 (6329) : 714 - 718
[2] MEDIATION BY NITRIC-OXIDE FORMATION IN THE PREOPTIC AREA OF ENDOTOXIN AND TUMOR NECROSIS FACTOR-INDUCED INHIBITION OF WATER-INTAKE IN THE RAT
CALAPAI, G
MAZZAGLIA, G
CILIA, M
ZINGARELLI, B
SQUADRITO, F
CAPUTI, AP
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1994, 111 (04) : 1328 - 1332
[3] EVIDENCE THAT NITRIC-OXIDE MODULATES DRINKING BEHAVIOR
CALAPAI, G
SQUADRITO, F
ALTAVILLA, D
ZINGARELLI, B
CAMPO, GM
CILIA, M
CAPUTI, AP
[J]. NEUROPHARMACOLOGY, 1992, 31 (08) : 761 - 764
[4] THE PERIVENTRICULAR ANTEROVENTRAL 3RD VENTRICLE (AV3V) - ITS RELATIONSHIP WITH THE SUBFORNICAL ORGAN AND NEURAL SYSTEMS INVOLVED IN MAINTAINING BODY-FLUID HOMEOSTASIS
JOHNSON, AK
[J]. BRAIN RESEARCH BULLETIN, 1985, 15 (06) : 595 - 601
[5] UP-REGULATION OF NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION TOGETHER WITH NOS ACTIVITY IN THE RAT HYPOTHALAMOHYPOPHYSEAL SYSTEM AFTER CHRONIC SALT LOADING - EVIDENCE OF A NEUROMODULATORY ROLE OF NITRIC-OXIDE IN ARGININE-VASOPRESSIN AND OXYTOCIN SECRETION
KADOWAKI, K
KISHIMOTO, J
LENG, G
EMSON, PC
[J]. ENDOCRINOLOGY, 1994, 134 (03) : 1011 - 1017
[6] ANGIOTENSIN-II RESPONSIVENESS OF RAT PARAVENTRICULAR AND SUBFORNICAL ORGAN NEURONS IN-VITRO
LI, Z
FERGUSON, AV
[J]. NEUROSCIENCE, 1993, 55 (01) : 197 - 207
[7] BIOSYNTHESIS OF NITRIC-OXIDE FROM L-ARGININE - A PATHWAY FOR THE REGULATION OF CELL-FUNCTION AND COMMUNICATION
MONCADA, S
PALMER, RMJ
HIGGS, EA
[J]. BIOCHEMICAL PHARMACOLOGY, 1989, 38 (11) : 1709 - 1715
[8] ANGIOTENSIN-II SENSITIVE NEURONS IN THE SUPRAOPTIC NUCLEUS, SUBFORNICAL ORGAN AND ANTEROVENTRAL THIRD VENTRICLE OF RATS INVITRO
OKUYA, S
INENAGA, K
KANEKO, T
YAMASHITA, H
[J]. BRAIN RESEARCH, 1987, 402 (01) : 58 - 67
[9] NADPH-DIAPHORASE (NITRIC-OXIDE SYNTHASE) STAINING IN THE RAT SUPRAOPTIC NUCLEUS IS ACTIVITY-DEPENDENT - POSSIBLE FUNCTIONAL IMPLICATIONS
POW, DV
[J]. JOURNAL OF NEUROENDOCRINOLOGY, 1992, 4 (04) : 377 - 380
[10] CENTRAL INHIBITION OF NITRIC-OXIDE SYNTHASE PREFERENTIALLY AUGMENTS RELEASE OF OXYTOCIN DURING DEHYDRATION
SUMMYLONG, JY
BUI, V
MANTZ, S
KOEHLER, E
WEISZ, J
KADEKARO, M
[J]. NEUROSCIENCE LETTERS, 1993, 152 (1-2) : 190 - 193

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