CALCIUM SIGNALING IN PLATELETS AND OTHER NONEXCITABLE CELLS

被引：56

作者：

SARGEANT, P ^{[1
]}

SAGE, SO ^{[1
]}

机构：

[1] UNIV CAMBRIDGE, PHYSIOL LAB, CAMBRIDGE CB2 3EG, ENGLAND

来源：

PHARMACOLOGY & THERAPEUTICS | 1994年 / 64卷 / 03期

关键词：

PLATELET; AGGREGATION; SECRETION; INTRACELLULAR FREE CALCIUM CONCENTRATION; INTRACELLULAR STORES; STORE-REGULATED CA2+ ENTRY;

D O I：

10.1016/0163-7258(94)90019-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

By virtue of their biological simplicity and widespread availability, platelets frequently have been used as a model system to study signal transduction. Such studies have revealed that changes in intracellular free calcium concentration are central to platelet functioning. The following article reviews current concepts of platelet structure and function, with particular emphasis on the mechanisms involved in platelet Ca2+ signalling.

引用

页码：395 / 443

页数：49

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