FEATURES OF AGE-RELATED MACULAR DEGENERATION IN A BLACK-POPULATION

被引：132

作者：

SCHACHAT, AP

HYMAN, L

LESKE, MC

CONNELL, AMS

WU, SY

机构：

[1] JOHNS HOPKINS UNIV,CTR PHOTOG READING,BALTIMORE,MD

[2] SUNY STONY BROOK,CTR COORDINATING,STONY BROOK,NY 11794

[3] MINIST HLTH,BRIDGETOWN,BARBADOS

来源：

ARCHIVES OF OPHTHALMOLOGY | 1995年 / 113卷 / 06期

关键词：

D O I：

10.1001/archopht.1995.01100060054032

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Objective: To report on the frequency of features of age-related macular degeneration in a black population based on fundus photograph gradings. Design: Population-based study. Setting: Barbados, West Indies. Study Population: Residents of Barbados, selected by a random sample of Barbados-born citizens, aged 40 to 84 years. Main Outcome Measure: Gradings from 30 degrees stereoscopic macular photographs. Results: Black participants (n=3444) completed examinations at the study site and had gradable macular photographs in both eyes. Drusen larger than 63 mu m occurred with comparable frequency in men and women. The frequency of small drusen decreased with age, while medium and large drusen were more common in older participants. Frequencies of all age-related macular degeneration-related characteristics were similar for men and women except for small drusen, which occurred more commonly in women. Confluent drusen and pigment atrophy also increased significantly with age. Exudative features occurred in 0.5% of the participants. Conclusions: This study provides population-based data on the frequency of features of age-related macular degeneration based on photographic gradings of a black population. Features of early age-related macular degeneration were common, but appeared at a lower frequency than has been reported for white populations. Exudative disease was infrequent, occurring in about one of 200 participants.

引用

页码：728 / 735

页数：8

共 13 条

[1]

Kahn H.A., Moorhead H.B., Statistics on Blindness in the Model Reporting Area 1969-1970, (1973)

[2]

Gibson J.M., Rosenthal A.R., Lavery J., A study of the prevalence of eye disease in the elderly in an English community, Trans Ophthalmol Soc U K, 104, pp. 196-203, (1985)

[3]

Martinez G.S., Campbell A.J., Reinken J., Allan B.C., Prevalence of ocular disease in a population study of subjects 65 years old and older, Am J Ophthalmol, 94, pp. 181-189, (1982)

[4]

Jonasson K., Thordarson K., Prevalence of ocular disease and blindness in a rural area in the eastern region of Iceland during 1980 through 1984, Acta Ophthalmol, 65, suppl 182, pp. 40-43, (1987)

[5]

Jampol L.M., Tielsch J., Race, macular degeneration, and the Macular Photocoagulation Study, Arch Ophthalmol, 110, pp. 1699-1700, (1992)

[6]

Gregor Z., Joffe L., Senile macular changes in the black African, Br J Ophthalmol, 62, pp. 547-550, (1978)

[7]

Sommer A., Tielsch J.M., Katz J., Racial differences in the cause-specific prevalence of blindness in East Baltimore, N Engl J Med, 325, pp. 1412-1417, (1991)

[8]

Kahn H.A., Leibowitz H.M., Ganley J.P., The Framingham Eye Study, I: outline and major prevalence findings, Am J Epidemiol, 106, pp. 17-32, (1977)

[9]

Klein B.E., Klein R., Cataracts and macular degeneration in older Americans, Arch Ophthalmol, 100, pp. 571-573, (1982)

[10]

Bressler N.M., Bressler S.B., West S.K., Fine S.L., Taylor H.R., The grading and prevalence of macular degeneration in Chesapeake Bay watermen, Arch Ophthalmol, 107, pp. 847-852, (1989)

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