ANTICANCER AND ANTIMICROBIAL GLYCOSIDES FROM IPOMOEA-BAHIENSIS

被引：24

作者：

BIEBER, LW ^{[1
]}

FILHO, AAS ^{[1
]}

LIMA, RMOC ^{[1
]}

CHIAPPETA, AD ^{[1
]}

DONASCIMENTO, SC ^{[1
]}

DESOUZA, IA ^{[1
]}

DEMELLO, JF ^{[1
]}

VEITH, HJ ^{[1
]}

机构：

[1] TH DARMSTADT, DEPT ORGAN CHEM & BIOCHEM, D-6100 DARMSTADT, FED REP GER

来源：

PHYTOCHEMISTRY | 1986年 / 25卷 / 05期

关键词：

D O I：

10.1016/S0031-9422(00)81557-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four new antimicrobial glycosides have been isolated from Ipomoea bahiensis. Spectroscopic properties and basic and acidic hydrolysis characterized them as derivatives of 11-hydroxyhexadecanoic and 11-hydroxytetradecanoic acid, glycosidically linked in the 11-position to a trisaccharide unit composed of glucose, rhamnose and fucose which is esterified by tiglic and 3-hydroxy-2-methylbutyric acid. One of these compounds revealed significant activity against Sarcoma 180 in mice.

引用

页码：1077 / 1081

页数：5

共 27 条

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