N-ACYLGLYCINES - GAS-CHROMATOGRAPHIC MASS-SPECTROMETRIC IDENTIFICATION AND DETERMINATION IN URINE BY SELECTED ION MONITORING

被引：24

作者：

GREGERSEN, N

KEIDING, K

KOLVRAA, S

机构：

[1] Research Laboratory for Metabolic Disorders, University Department of Clinical Chemistry, Aarhus Kommunehospital, Aarhus

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 10期

关键词：

D O I：

10.1002/bms.1200061007

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Eleven biologically interesting N‐acylglycines have been synthesized and the gas chromatographic and mass spectrometric properties of their trimethylsilyl derivatives studied. A sharp and reproducible gas chromatographic peak could be obtained for each N‐acylglycine as the N, O‐bis‐(trimethylsilyl)‐N‐acylglycine. By the use of these derivatives a sensitive and specific selected ion monitoring method for the determination of N‐acylglycines in human urine has been developed. Copyright © 1979 Heyden & Son Ltd

引用

页码：439 / 443

页数：5

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