CHARACTERIZATION OF A PLASMA FACTOR HAVING OPIATE AND IMMUNOACTIVITY LIKE BETA-ENDORPHIN

被引：7

作者：

HO, WKK

KWOK, KY

LAM, S

机构：

[1] Department of Biochemistry The Chinese University of Hong Kong, Shatin, New Territories

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)91816-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A factor from human plasma having opiate-like activity was characterized in the present study. In addition to its ability to inhibit the binding of [3H]-methionine-enkephalin to opiate receptors, it also cross-reacted with two β-endorphin specific anti-sera. Compared with β-endorphin, the plasma factor had a shorter action on inhibiting the contraction of the guinea pig ileum. By gel-filtration chromatography, the size of this factor was intermediate between that of β-endorphin and methionine-enkephalin. © 1979.

引用

页码：448 / 454

页数：7

共 19 条

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