EVIDENCE FOR THE SECRETION OF INHIBIN-LIKE IMMUNOREACTIVITY FROM CULTURED HUMAN ADRENAL-CELLS

被引：22

作者：

HAJI, M

NISHI, Y

TANAKA, S

OHASHI, M

SEKIYA, K

HASEGAWA, Y

IGARASHI, M

SASAMOTO, S

NAWATA, H

机构：

[1] GUNMA UNIV,SCH MED,DEPT OBSTET & GYNECOL,MAEBASHI,GUNMA 371,JAPAN

[2] TOKYO UNIV AGR & TECHNOL,VET PHYSIOL LAB,FUCHU,TOKYO 183,JAPAN

来源：

JOURNAL OF ENDOCRINOLOGY | 1991年 / 128卷 / 03期

关键词：

D O I：

10.1677/joe.0.128R013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We have studied the production and release of inhibin-like immunoreactivity in the human adrenal gland. Extract of human adrenal glands showed a displacement curve paralleled with the inhibin standard. Inhibin-like immunoreactivity contents in the adrenal gland was 1893 +/- 474 (mean +/- S.D.) IU/g wet weight tissue. ACTH stimulated the secretion of inhibin-like immunoreactivity as well as cortisol and aldosterone in a dose-dependent manner in the cultured adrenal cells. These results indicate that the human adrenal gland produces and secretes inhibin-like peptide in response to ACTH.

引用

页码：R13 / R16

页数：4

共 18 条

[1] Baker H W, 1976, Recent Prog Horm Res, V32, P429
[2] SERUM IMMUNOREACTIVE INHIBIN LEVELS BEFORE AND AFTER LUTEECTOMY IN THE CYNOMOLGUS MONKEY (MACACA-FASCICULARIS)
BASSETI, SG
WINTERS, SJ
KEEPING, HS
ZELEZNIK, AJ
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 70 (03) : 590 - 594
[3] ALPHA-INHIBIN GENE-EXPRESSION OCCURS IN THE OVINE ADRENAL-CORTEX, AND IS REGULATED BY ADRENOCORTICOTROPIN
CRAWFORD, RJ
HAMMOND, VE
EVANS, BA
COGHLAN, JP
HARALAMBIDIS, J
HUDSON, B
PENSCHOW, JD
RICHARDS, RI
TREGEAR, GW
[J]. MOLECULAR ENDOCRINOLOGY, 1987, 1 (10) : 699 - 706
[4] EVIDENCE FOR INHIBIN-LIKE ACTIVITY IN BOVINE FOLLICULAR-FLUID
DEJONG, FH
SHARPE, RM
[J]. NATURE, 1976, 263 (5572) : 71 - 72
[5] RADIOIMMUNOASSAY OF INHIBIN IN VARIOUS MAMMALS
HAMADA, T
WATANABE, G
KOKUHO, T
TAYA, K
SASAMOTO, S
HASEGAWA, Y
MIYAMOTO, K
IGARASHI, M
[J]. JOURNAL OF ENDOCRINOLOGY, 1989, 122 (03) : 697 - 704
[6] CHANGES IN SERUM CONCENTRATIONS OF INHIBIN IN CYCLIC PIGS
HASEGAWA, Y
MIYAMOTO, K
IWAMURA, S
IGARASHI, M
[J]. JOURNAL OF ENDOCRINOLOGY, 1988, 118 (02) : 211 - 219
[7] ALPHA-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE INHIBITS STEROIDOGENESIS IN CULTURED HUMAN ADRENAL-CELLS
HIGUCHI, K
NAWATA, H
KATO, K
IBAYASHI, H
MATSUO, H
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 62 (05) : 941 - 944
[8] HETERODIMERS AND HOMODIMERS OF INHIBIN SUBUNITS HAVE DIFFERENT PARACRINE ACTION IN THE MODULATION OF LUTEINIZING HORMONE-STIMULATED ANDROGEN BIOSYNTHESIS
HSUEH, AJW
DAHL, KD
VAUGHAN, J
TUCKER, E
RIVIER, J
BARDIN, CW
VALE, W
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (14) : 5082 - 5086
[9] EVIDENCE THAT THE BOVINE OVARY SECRETES LARGE AMOUNTS OF MONOMERIC INHIBIN ALPHA-SUBUNIT AND ITS ISOLATION FROM BOVINE FOLLICULAR-FLUID
KNIGHT, PG
BEARD, AJ
WRATHALL, JHM
CASTILLO, RJ
[J]. JOURNAL OF MOLECULAR ENDOCRINOLOGY, 1989, 2 (03) : 189 - 200
[10] GONADAL AND EXTRAGONADAL EXPRESSION OF INHIBIN-ALPHA, INHIBIN-BETA-A, AND INHIBIN-BETA-B SUBUNITS IN VARIOUS TISSUES PREDICTS DIVERSE FUNCTIONS
MEUNIER, H
RIVIER, C
EVANS, RM
VALE, W
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (01) : 247 - 251

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