MOLECULAR STRATEGIES IN GENETIC DIAGNOSIS OF TRANSTHYRETIN-RELATED HEREDITARY AMYLOIDOSIS

被引：38

作者：

FERLINI, A

FINI, S

SALVI, F

PATROSSO, MC

VEZZONI, P

FORABOSCO, A

机构：

[1] BELLARIA HOSP, DEPT NEUROL, BOLOGNA, ITALY

[2] CNR, IST TECNOL BIOMED AVANZATE, I-20133 MILAN, ITALY

来源：

FASEB JOURNAL | 1992年 / 6卷 / 10期

关键词：

TRANSTHYRETIN GENE; HEREDITARY AMYLOIDOSIS; RG-PCR SEQUENCE ANALYSIS;

D O I：

10.1096/fasebj.6.10.1353040

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transthyretin-related hereditary (TTR) amyloidoses represent a clinically heterogeneous group of diseases associated with various point mutations of the TTR gene. We propose a molecular strategy for the diagnosis of this group of disorders.

引用

页码：2864 / 2866

页数：3

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