INTRACRANIAL ARTERIAL-OCCLUSION ASSOCIATED WITH HIGH-ACTIVITY I-125 BRACHYTHERAPY FOR GLIOBLASTOMA

被引：17

作者：

BERNSTEIN, M

LUMLEY, M

DAVIDSON, G

LAPERRIERE, N

LEUNG, P

机构：

[1] TORONTO HOSP, DIV NEUROPATHOL, TORONTO M5T 2S8, ON, CANADA

[2] UNIV TORONTO, PRINCESS MARGARET HOSP, DEPT RADIAT ONCOL, TORONTO, ON, CANADA

[3] UNIV TORONTO, PRINCESS MARGARET HOSP, DEPT PHYS, TORONTO, ON, CANADA

来源：

JOURNAL OF NEURO-ONCOLOGY | 1993年 / 17卷 / 03期

关键词：

BRACHYTHERAPY; RADIATION-INDUCED STROKE; COMPLICATIONS; EXPERIMENTAL THERAPY; BRAIN TUMOR;

D O I：

10.1007/BF01049980

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We describe two patients who developed devastating strokes due to intracranial arterial occlusion 15 weeks and 97 weeks following high dose stereotactic iodine-125 brachytherapy for glioblastoma multiforme. In both cases the occlusion was within the implant volume at points receiving 110-281 Gy and there was no other evidence of significant atherosclerosis in the patients. We therefore conclude that these complications were a direct result of the brachytherapy. The phenomenon of radiation-induced occlusion of large cerebral arteries is reviewed.

引用

页码：253 / 260

页数：8

共 40 条

[1] RADIATION-INDUCED CORONARY OBSTRUCTIVE ATHEROSCLEROSIS AND SUDDEN-DEATH IN A TEENAGER [J].