STROMATOLYSIS OF SHEEP ERYTHROCYTES BY TRITON-X-100

被引:1
作者
COONEY, DA
DRAKE, JC
机构
[1] Laboratory of Chemical Pharmacology, National Cancer Institute, Bethesda
[2] Microbiological Associates, Inc., Bethesda, Md 20014
关键词
D O I
10.1016/0014-4827(69)90285-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Sheep erythrocytes have been shown to be susceptible to the stromatolytic effects of the detergent, Triton-X-100. This susceptibility is pH and temperature dependent. A number of inhibitors of Triton-X-100 stromatolysis have been studied, among them phospholipids, pump poisons, chelating agents and proteinaceous substances. As a result of Triton-X-100 stromatolysis, a molybdenum-blue, ninhydrin positive material is released from the erythrocyte. It is concluded that Triton-X-100 falls into the category of specific hemolysins. © 1969.
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页码:11 / &
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