USE OF THE 2,4-DINITROBENZYL PROTECTING GROUP IN THE SYNTHESIS OF PHOSPHORODITHIOATE ANALOGS OF OLIGODEOXYRIBONUCLEOTIDES

被引：41

作者：

PORRITT, GM ^{[1
]}

REESE, CB ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL,DEPT CHEM,LONDON WC2R 2LS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(00)88796-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The putative intermediate bis(1,2,4-triazolide) derivative (5) is used in the stepwise synthesis in solution of the phosphorodithioate analogue (10) of thymidylyl-(3′→5′)-thymidylyl-(3′→5′)-thymidine; the 2,4-dinitrobenzyl (Dnb) group is used to protect phosphorodithioate internucleotide linkages. © 1990.

引用

页码：1319 / 1322

页数：4

共 19 条

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