DYNAMIC IMAGING WITH T(2)ASTERISK CONTRAST USING U-FLARE

被引:16
作者
NORRIS, DG
HOEHNBERLAGE, M
WITTLICH, F
BACK, T
LEIBFRITZ, D
机构
[1] Fachbereich Chemie, Universität Bremen
[2] Max-Planck-Institut für neurologische Forschung, D-50866 Köln
关键词
U-FLARE; T(2)ASTERISK CONTRAST; PERFUSION;
D O I
10.1016/0730-725X(93)90210-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Dynamic changes in T2* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T2* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO2 values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T2*, and thus has application in imaging of both perfusion and functional activation.
引用
收藏
页码:921 / 924
页数:4
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