SPECIFICITY OF IGG-CLASS AND IGM-CLASS SMOOTH-MUSCLE ANTIBODY IN THE SERA OF PATIENTS WITH MULTIPLE-SCLEROSIS AND ACTIVE CHRONIC HEPATITIS

被引：18

作者：

MCMILLAN, SA ^{[1
]}

HAIRE, M ^{[1
]}

机构：

[1] QUEENS UNIV BELFAST,DEPT MICROBIOL & IMMUNOL,BELFAST BT12 6BN,ANTRIM,NORTH IRELAND

来源：

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY | 1979年 / 14卷 / 02期

关键词：

D O I：

10.1016/0090-1229(79)90148-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The specificity of IgG and IgM smooth muscle antibodies (SMA) present in sera of patients with multiple sclerosis (MS) and active chronic hepatitis (ACH) was investigated using the indirect immunofluorescent technique combined with studies on cultured cells treated with cytotoxic drugs. IgM class of SMA was detected in both the MS and ACH sera and appeared to react with a component of cellular intermediate filaments. In addition the ACH sera contained IgG class of SMA of anti-actin specificity. © 1979.

引用

页码：256 / 263

页数：8

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