PEPTIDIC ALPHA-HYDROXY PHOSPHINYLS C-TERMINAL MODIFICATION METHODOLOGY

被引：119

作者：

PATEL, DV

RIELLYGAUVIN, K

RYONO, DE

机构：

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(00)97904-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Compound 4 is a suitable intermediate for making C-terminal mortifications of the transition state mimicking "α-hydroxy-phosphinyl" moiety. Its preparmion and application are described. © 1990.

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页码：5591 / 5594

页数：4

相关论文

共 7 条

[1] THE SYNTHESIS AND CONFIGURATIONAL STABILITY OF DIFFERENTIALLY PROTECTED BETA-HYDROXY-ALPHA-AMINO ALDEHYDES
GARNER, P
PARK, JM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (12) : 2361 - 2364
[2] DOES SALT FORMATION INCREASE THE FREQUENCY OF SPONTANEOUS RESOLUTION
JACQUES, J
LECLERCQ, M
BRIENNE, MJ
[J]. TETRAHEDRON, 1981, 37 (09) : 1727 - 1733
[3] KETOMETHYLDIPEPTIDES .1. A NEW CLASS OF ANGIOTENSIN CONVERTING ENZYME-INHIBITORS
NATARAJAN, S
GORDON, EM
SABO, EF
GODFREY, JD
WELLER, HN
PLUSCEC, J
ROM, MB
CUSHMAN, DW
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 124 (01) : 141 - 147
[4] PREPARATION OF PEPTIDIC ALPHA-HYDROXY PHOSPHONATES A NEW CLASS OF TRANSITION-STATE ANALOG RENIN INHIBITORS
PATEL, DV
RIELLYGAUVIN, K
RYONO, DE
[J]. TETRAHEDRON LETTERS, 1990, 31 (39) : 5587 - 5590
[5] HYDROXYETHYLAMINE ANALOGS OF THE P17/P24 SUBSTRATE CLEAVAGE SITE ARE TIGHT-BINDING INHIBITORS OF HIV PROTEASE
RICH, DH
GREEN, J
TOTH, MV
MARSHALL, GR
KENT, SBH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (05) : 1285 - 1288
[6] RICH DH, IN PRESS COMPREHENSI, V2
[7] RYONO DE, 1985, PEPTIDES STRUCTURE F, P739