A NOVEL REARRANGEMENT REACTION CONVERSION OF 3-(CHLOROMETHYL)AZETIDIN-2-ONES TO AZETIDINE-3-CARBOXYLIC ACID-ESTERS

被引：10

作者：

BARTHOLOMEW, D

STOCKS, MJ

机构：

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)92310-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Transformation of 3-(chloromethyl)azetidin-2-ones to azetidine-3-carboxylic acid esters is described. The readily available 3-(chloromethyl)azetidin-2-ones rearranged in good yields to azetidine-3-carboxylic acid esters on treatment with alkoxides. An alternative ring opening - ring closure procedure is also identified.

引用

页码：4795 / 4798

页数：4

共 5 条

[1]

FLETCHER SR, 1984, J CHEM SOC CHEM COMM, P903

[2] THE SYNTHESIS OF 3-CHLORO-2-CHLOROMETHYL-1-PROPENE FROM PENTAERYTHRITO [J].