BLOOD-TESTS FOR DETECTION OF ALCOHOLIC CAUSE OF ACUTE-PANCREATITIS

被引:40
作者
JAAKKOLA, M
SILLANAUKEE, P
LOF, K
KOIVULA, T
NORDBACK, I
机构
[1] TAMPERE UNIV HOSP, DEPT SURG, SF-33250 TAMPERE, FINLAND
[2] UNIV TAMPERE, DEPT CLIN MED, SF-33101 TAMPERE, FINLAND
[3] TAMPERE UNIV HOSP, DEPT CLIN CHEM, TAMPERE, FINLAND
[4] ALKO LTD, BIOMED RES CTR, TAMPERE, FINLAND
关键词
D O I
10.1016/S0140-6736(94)92470-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We investigated the ability of various blood markers to detect an alcoholic cause of acute pancreatitis. Serum carbohydrate-deficient transferrin (CDT) was significantly correlated with reported 2 month and 7 day ethanol consumptions and was significantly higher in 42 patients with alcoholic acute pancreatitis and in 24 patients with possibly alcoholic acute pancreatitis than in 20 patients with non-alcoholic disease. At a cutoff over 17 U/L, the specificity of CDT was 100% and the sensitivity was 75% to detect an alcoholic cause of acute pancreatitis. The lipase/amylase ratio index, erythrocyte mean corpuscular volume, and gamma glutamyl transferase could not distinguish alcoholic from non-alcoholic acute pancreatitis.
引用
收藏
页码:1328 / 1329
页数:2
相关论文
共 10 条
[1]  
CHICK J, 1981, LANCET, V1, P1249
[2]   LIPASE AMYLASE RATIO - A NEW INDEX THAT DISTINGUISHES ACUTE EPISODES OF ALCOHOLIC FROM NONALCOHOLIC ACUTE-PANCREATITIS [J].
GUMASTE, VV ;
DAVE, PB ;
WEISSMAN, D ;
MESSER, J .
GASTROENTEROLOGY, 1991, 101 (05) :1361-1366
[3]   PREVALENCE, DETECTION, AND TREATMENT OF ALCOHOLISM IN HOSPITALIZED-PATIENTS [J].
MOORE, RD ;
BONE, LR ;
GELLER, G ;
MAMON, JA ;
STOKES, EJ ;
LEVINE, DM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 261 (03) :403-407
[4]  
NORONHA M, 1981, AM J GASTROENTEROL, V76, P114
[5]   SERUM AMYLASE AND LIPASE CONCENTRATIONS AND LIPASE AMYLASE RATIO IN ASSESSMENT OF ETIOLOGY AND SEVERITY OF ACUTE-PANCREATITIS [J].
PEZZILLI, R ;
BILLI, P ;
MIGLIOLI, M ;
GULLO, L .
DIGESTIVE DISEASES AND SCIENCES, 1993, 38 (07) :1265-1269
[6]   CDT BY ANION-EXCHANGE CHROMATOGRAPHY FOLLOWED BY RIA AS A MARKER OF HEAVY DRINKING AMONG MEN [J].
SILLANAUKEE, P ;
SEPPA, K ;
LOF, K ;
KOIVULA, T .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1993, 17 (02) :230-233
[7]  
Sillanaukee P, 1992, SUOM LAAKARILEHTI, V31, P2919
[8]  
STIBLER H, 1991, CLIN CHEM, V37, P2029
[9]  
STIBLER H, 1991, ALCOHOL ALCOHOLISM, P451
[10]  
Stibler H, 1980, Subst Alcohol Actions Misuse, V1, P247