RIBONUCLEIC ACID BIOSYNTHESIS IN ADULT AND INFANT RAT BRAIN IN VITRO

被引：21

作者：

OTOH, T

QUASTEL, JH

机构：

[1] Kinsmen Laboratories of Neurological Research, University of British Columbia, Vancouver, BC

来源：

SCIENCE | 1969年 / 164卷 / 3875期

关键词：

D O I：

10.1126/science.164.3875.79

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The rate of biosynthesis of ribonucleic acid (as judged by the rate of incorporation of uridine into ribonucleic acid) in infant and adult rat brain cortex slices, incubated aerobically in the presence of various substrates, is directly proportional to the adenosine triphosphate concentration. This suggests that the adenosine triphosphate concentration is one of the factors involved in the control of ribonucleic acid biosynthesis in infant and adult rat brain. Acetoacetate or β-hydroxybutyrate is about 70 percent as effective as glucose, with both infant and adult brain, for the promotion of ribonucleic acid biosynthesis, but they are considerably more effective than succinate in infant brain than in adult brain.

引用

页码：79 / &

共 9 条

[1]

BERGMEYER HU, 1965, METHODS ENZYMATIC ED, P551

[2]

GREENGARD P, 1965, METHOD ENZYMAT AN, P551

[3] BIOSYNTHESIS OF RIBONUCLEIC ACID IN RAT BRAIN SLICES [J].