SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME 3-BENZYLIDENECHROMAN-4-ONES, 3-BENZYLIDENETHIOCHROMAN-4-ONES AND 2-BENZYLIDENE-1-TETRALONES

被引：111

作者：

ALNAKIB, T

BEZJAK, V

MEEGAN, MJ

CHANDY, R

机构：

[1] TRINITY COLL DUBLIN,DEPT PHARMACEUT CHEM,18 SHREWSBURY RD,DUBLIN 4,IRELAND

[2] UNIV KUWAIT,FAC MED,DEPT PHARMACOL & MICROBIOL,SAFAT 13110,KUWAIT

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1990年 / 25卷 / 05期

关键词：

2-benzylidene-1-tetralones; 3-benzylidenechroman-4-ones; 3-benzylidenethiochroman-4-ones; antifungal activity;

D O I：

10.1016/0223-5234(90)90010-Z

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of 3-benzylidenechroman-4-ones, 3-benzylidenethiochroman-4-ones and 2-benzylidene-1-tetralones have been synthesised and tested for their in vitro antifungal activity. Some of them were inactive; others displayed good activity against Cryptococcus neoformans, Torulopsis glabrata and Trichosporon cutaneum. © 1990.

引用

页码：455 / 462

页数：8

共 47 条

[1] ALNAKIB T, 1987, J CHEM RES-S, P322
[2] ALNAKIB T, 1987, J CHEM RES M, P2743
[3] [Anonymous], 1980, MANUAL CLIN MICROBIO
[4] Chromanon and chromanol
Arndt, F
Kallner, G
[J]. BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1924, 57 : 202 - 206
[5] Thioflavanone, thiochromanone and chromanole.
Arndt, F
[J]. BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1923, 56 : 1269 - 1279
[6] AZZOLINA O, 1975, GAZZ CHIM ITAL, V105, P971
[7] BEIRNE JJ, 1977, P R IR ACAD, V77, P331
[8] BOHLER P, 1967, TETRAHEDRON LETT, P3479
[9] CANILINI G, 1967, ANN CHIM, V57, P1045
[10] CHATTERJEA JN, 1978, NATL ACAD SCI LETT, V1, P391

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