METABOLIC STABILITY OF NON-HISTONE CHROMOSOMAL-PROTEINS IN 2 DIFFERENT CLASSES OF DEVELOPING RAT-BRAIN NUCLEI

被引：12

作者：

STAMBOLOVA, MA ^{[1
]}

ANGELOVA, AA ^{[1
]}

TSANEV, RG ^{[1
]}

机构：

[1] BULGARIAN ACAD SCI,INST MOLEC BIOL,BU-1113 SOFIA,BULGARIA

来源：

CELL DIFFERENTIATION | 1979年 / 8卷 / 03期

关键词：

D O I：

10.1016/0045-6039(79)90046-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The metabolic behaviour of NHCP was studied in rat brain nuclei from fully differentiated cells and in nuclei from still differentiating cells. Eight-day-old rats were injected intracisternally with [14C]thymidine and [3H]tryptorphan and the 3H/14C ratio of the chromatin was followed for a period of 33 days. It was found that in the fraction of differentiated cells this ratio remained unchanged, showing the presence of metabolically stable NHCP. At the same time in the fraction containing nondifferentiated cells a substantial part of the NHCP was turned over, which was indicated by a sharp decrease in their 3H/14C ratio with time. © 1979.

引用

页码：195 / 202

页数：8

共 24 条

[1] AUTORADIOGRAPHIC AND HISTOLOGICAL STUDIES OF POSTNATAL NEUROGENESIS .4. CELL PROLIFERATION AND MIGRATION IN ANTERIOR FOREBRAIN, WITH SPECIAL REFERENCE TO PERSISTING NEUROGENESIS IN OLFACTORY BULB [J].

ALTMAN, J .

JOURNAL OF COMPARATIVE NEUROLOGY, 1969, 137 (04) :433-&

[2]

ALTMAN J, 1969, HDB NEUROCHEMISTRY, V2, P137

[3]

ANDERSON LA, 1973, ANAL BIOCHEM, V53, P173

[4] FRACTIONATION OF NUCLEI FROM BRAIN BY ZONAL CENTRIFUGATION AND A STUDY OF RIBONUCLEIC-ACID POLYMERASE-ACTIVITY IN VARIOUS CLASSES OF NUCLEI [J].

AUSTOKER, J ;

MATHIAS, AP ;

COX, D .

BIOCHEMICAL JOURNAL, 1972, 129 (05) :1139-&

[5] SYNTHESIS OF ACIDIC CHROMOSOMAL PROTEINS DURING CELL CYCLE OF HELA S-3 CELLS .2. KINETICS OF RESIDUAL PROTEIN-SYNTHESIS AND TRANSPORT [J].

BORUN, TW ;

STEIN, GS .

JOURNAL OF CELL BIOLOGY, 1972, 52 (02) :308-&

[6] RELATIONSHIP BETWEEN DNA-SYNTHESIS AND SYNTHESIS OF NUCLEAR PROTEINS IN RAT-BRAIN DURING DEVELOPMENT [J].

BURDMAN, JA .

JOURNAL OF NEUROCHEMISTRY, 1972, 19 (06) :1459-&

[7] ESTIMATION OF DEOXYRIBONUCLEIC ACID IN PRESENCE OF SIALIC ACID - APPLICATION TO ANALYSIS OF HUMAN GASTRIC WASHINGS [J].

CROFT, DN ;

LUBRAN, M .

BIOCHEMICAL JOURNAL, 1965, 95 (03) :612-&

[8]

DEVELLIS J, 1970, CELL DIFFER, P529

[9] METABOLIC BEHAVIOR OF NONHISTONE CHROMOSOMAL-PROTEINS IN PROLIFERATING AND IN RESTING FIBROBLASTS [J].

DJONDJUROV, LP ;

IVANOVA, EC ;

TSANEV, RG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 77 (03) :545-553

[10] QUANTITATIVE ANALYSIS OF CELL PROLIFERATION AND DIFFERENTIATION IN CORTEX OF POSTNATAL MOUSE CEREBELLUM [J].

FUJITA, S .

JOURNAL OF CELL BIOLOGY, 1967, 32 (02) :277-+

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