EQUILIBRIUM SWELLING BEHAVIOR OF PH-SENSITIVE HYDROGELS

被引：424

作者：

BRANNONPEPPAS, L ^{[1
]}

PEPPAS, NA ^{[1
]}

机构：

[1] PURDUE UNIV,SCH CHEM ENGN,W LAFAYETTE,IN 47907

来源：

CHEMICAL ENGINEERING SCIENCE | 1991年 / 46卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0009-2509(91)80177-Z

中图分类号：

TQ [化学工业];

学科分类号：

0817 [化学工程与技术];

摘要：

The equilibrium swelling behavior of hydrogels sensitive to pH or ionic strength changes of the swelling medium was studied using new structural models which are based on the Flory-Huggins thermodynamic theory, the rubber elasticity theory, and ionic interaction deviations therefrom. The number average molecular weight between crosslinks was related to equilibrium swelling characteristics, the thermodynamic compatability of the polymer-swelling agent system, the ionic charges, the pK(a) of the ionizable polymer moieties, and the pH and ionic strength of the surrounding medium. The models have predictive, correlative and design capabilities.

引用

收藏

页码：715 / 722

页数：8

相关论文

共 22 条

[1]

PHASE-TRANSITIONS IN CROSS-LINKED GELS OF NATURAL POLYMERS [J].

AMIYA, T ;

TANAKA, T .

MACROMOLECULES, 1987, 20 (05) :1162-1164

[2]

ANDRADE JD, 1976, ACS S SERIES, V31

[3]

CARTLIDGE S A, 1987, Journal of Controlled Release, V4, P265, DOI 10.1016/0168-3659(87)90018-6

[4]

INFLUENCE OF PREFERENTIAL SOLVATION ON THE INTERPOLYMER COMPLEX-FORMATION BETWEEN METHACRYLIC-ACID METHACRYLAMIDE COPOLYMER AND POLYVINYL PYRROLIDONE) [J].

CHATTERJEE, SK ;

MALHOTRA, A ;

YADAV, D .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1986, 24 (10) :2591-2597

[5]

HYDROPHILIC GELS BASED ON COPOLYMERS OF 2-HYDROXYETHYL METHACRYLATE WITH METHACRYLAMIDE AND ACRYLAMIDE [J].

DUSEK, K ;

JANACEK, J .

JOURNAL OF APPLIED POLYMER SCIENCE, 1975, 19 (11) :3061-3075

[6]

POLYMER COMPATIBILITY AND INTERPOLYMER ASSOCIATION IN THE POLY(ACRYLIC ACID) POLYACRYLAMIDE WATER TERNARY-SYSTEM [J].

EUSTACE, DJ ;

SIANO, DB ;

DRAKE, EN .

JOURNAL OF APPLIED POLYMER SCIENCE, 1988, 35 (03) :707-716

[7]

Statistical mechanics of cross-linked polymer networks II Swelling [J].

Flory, PJ ;

Rehner, J .

JOURNAL OF CHEMICAL PHYSICS, 1943, 11 (11) :521-526

[8]

CHEMICAL ASPECTS OF GEL EXTRACTION [J].

GEHRKE, SH ;

ANDREWS, GP ;

CUSSLER, EL .

CHEMICAL ENGINEERING SCIENCE, 1986, 41 (08) :2153-2160

[9]

DEFORMATIONAL, SWELLING, AND POTENTIOMETRIC BEHAVIOR OF IONIZED POLY(METHACRYLIC ACID) GELS .2. EXPERIMENTAL RESULTS [J].

HASA, J ;

ILAVSKY, M .

JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 1975, 13 (02) :263-274

[10]

SYNTHESIS AND PROPERTIES OF POLYMERIC HYDROGELS [J].

HEITZ, W ;

KRAPPITZ, W ;

STUTZELBILBAO, C ;

NEUMANN, B .

ANGEWANDTE MAKROMOLEKULARE CHEMIE, 1984, 123 (AUG) :147-173