MUTATIONS AT GLU-32 AND HIS-39 IN THE EPSILON-SUBUNIT OF THE ESCHERICHIA-COLI F1F0 ATP SYNTHASE AFFECT ITS INHIBITORY PROPERTIES

被引：20

作者：

LAROE, DJ ^{[1
]}

VIK, SB ^{[1
]}

机构：

[1] SO METHODIST UNIV,DEPT BIOL SCI,DALLAS,TX 75275

来源：

JOURNAL OF BACTERIOLOGY | 1992年 / 174卷 / 02期

关键词：

D O I：

10.1128/jb.174.2.633-637.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A collection of amino acid substitutions at residues Glu-32 and His-39 in the epsilon-subunit of the Escherichia coli F1F0 ATP synthase has been constructed by cassette mutagenesis. Substitutions for residue Glu-32 appeared to cause abnormal inhibition of membrane-bound F1 ATPase activity, and replacement of His-39 by Arg, Val, and Pro affected F1F0 interactions.

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页码：633 / 637

页数：5

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